Stroke and mental health intertwine significantly, with stroke survivors facing heightened risks of developing mental health disorders like depression, anxiety, and post-traumatic stress disorder (PTSD). These conditions profoundly influence recovery, quality of life, and functional outcomes post-stroke. Conversely, mental health issues may exacerbate stroke risk factors and impede treatment adherence and rehabilitation progress. Addressing stroke survivors’ mental health necessitates a multidisciplinary approach integrating psychiatric care, psychological support, and social services into stroke rehabilitation. Early identification, intervention, and ongoing support are paramount for optimizing mental health outcomes and overall stroke recovery, underscoring the importance of holistic care in stroke management.