Potential ways to improve wound healing include stem cell therapy. Topics covered in sessions include several types of stem cells, including pluripotent and mesenchymal stem cells, and how they may be used to treat wounds. Approaches to tissue healing that involve immunomodulation and paracrine signaling are discussed. A thorough grasp of stem cell treatment for wound healing is provided by the exploration of clinical studies, results, and safety issues. Healthcare practitioners can obtain new insights into treatment options that could reduce scarring, accelerate wound healing, and enhance patient outcomes for patients with difficult and persistent wounds by clarifying these mechanisms and their practical applications.