Certain individuals with psoriasis, a persistent skin ailment marked by red, scaly skin patches, may develop psoriatic arthritis (PsA), a chronic inflammatory arthritis. Usually, psoriatic arthritis develops in people who already have psoriasis, but it can also happen to people who have never had skin problems before. PsA is categorized as an autoimmune illness in which the immune system of the body unintentionally targets healthy tissues, causing inflammation and tissue damage to surrounding tissues and joints. An inflammatory condition affecting the synovium, the lining of the joints, is rheumatoid arthritis (RA), a long-term autoimmune illness. In rheumatoid arthritis (RA), the body’s immune system misinterprets healthy tissues, especially the synovium, causing discomfort, swelling, and eventually damage to the surrounding tissues and joints.