Pain management in rheumatic disorders refers to a holistic strategy to treating pain caused by autoimmune and inflammatory conditions affecting the musculoskeletal system, which are collectively known as rheumatic diseases. These diseases include rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, psoriatic arthritis, and ankylosing spondylitis. Pain is a typical symptom of rheumatic disorders, and it can have a substantial influence on a person’s quality of life, mobility, and general health. Effective pain management solutions seek to lower pain intensity, improve physical function, raise quality of life, and increase overall patient well-being.