Neuro-oncology integrates cutting-edge research with clinical care to tackle the complexities of brain and spinal tumor’s. Advances in molecular biology and genetics have revolutionized tumor classification and treatment stratification, allowing for tailored therapies based on tumor characteristics. Clinical trials explore novel treatment modalities, including immunotherapy and targeted agents, aiming to improve outcomes and quality of life for patients. Additionally, supportive care addresses the unique needs of patients and their families throughout the treatment journey. Despite challenges, neuro-oncology offers hope through innovative approaches and collaborative efforts aimed at combating these devastating diseases.