Farida S Rakhimova

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Title: Case of treatment of solid pseudopapillary pancreatic tumor

Solid pseudopapillary tumor of the pancreas, accounting for less than 3% of all pancreatic neoplasms, predominantly affects young women between the ages of 20 and 30. The prognosis for this condition is generally optimistic, as more than 85% of patients experience a complete cure following successful tumor resection. A clinical case from this publication illustrates the outcomes of surgical intervention in a patient with a malignant pancreatic tumor. The patient, known as M., born in 1998, received inpatient treatment at the prestigious I.K. Akhunbaeva National Hospital of the Ministry of Health of the Kyrgyz Republic from January 12, 2015, to January 26, 2015, presenting with a pancreatic head lesion discovered during surgery. Consequently, the decision was made to extend the surgical procedure. Subsequent histopathological examination confirmed the presence of a solid pseudopapillary tumor. Further immunohistochemical analysis identified positive expressions of synaptophysin, vimentin, neuron-specific enolase, B-catenin (nuclear reaction), PR, CK18, and CD10 in the tumor cells, assisting in characterizing the lesion histologically. This rare tumor type typically remains asymptomatic and is often incidentally detected or discovered upon reaching a significant size. Remarkably, the patient in this case displayed a favorable clinical progression without any indicators of disease advancement or recurrence over the seven-year post-treatment follow-up period. In conclusion, solid pseudopapillary tumor signifies a rare yet highly specialized malignant growth that predominantly emerges in young females. The clinical narrative depicted in this case study underscores the generally positive nature of this condition.


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